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  • 研究・開発
  • 研究ソリューション
    • ゲノム解析
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  • Next-Generation Biologics
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    • Next-Generation Biologics
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Next-Generation Biologics

Addressing modern biotherapeutic development challenges with advanced discovery, characterization, and testing solutions

Based on recent progress, next-generation biologics offer the promise to address or treat complex diseases. Success requires innovative solutions to overcome the challenges encountered with these next-generation biologics, including multi-specific antibodies, antibody-drug conjugates (ADCs), and RNA therapeutics / vaccines, to accomplish specificity, efficacy, and safety. This need for innovation has driven the rise in various engineering and modification approaches to standard antibody and RNA modalities for various disorders from cancer and autoimmune diseases to neurological and ophthalmic conditions.

Multi-specific antibodies such as bispecific antibodies (BsAbs) and ADCs provide a more multivalent and precise approach against two or more targets, whilst mRNA vaccines provide flexibility with the ability to efficiently deliver mRNA for rapid uptake.

Improve your next-generation biologics development and characterization with our solutions and products that can support your research in areas of cell line and assay development, tumor cell targeting, ex vivo and in vivo testing, structural and functional characterization, followed by data management and analysis.

For research use only. Not for use in diagnostic procedures.

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Explore our solutions

Bispecific antibodies Antibody drug conjugates RNA vaccines and therapeutics

Bispecific antibodies

Unlock the power of dual targeting with our BsAb solutions that can help design, engineer, and optimize your antibody therapeutic to target two distinct sites / markers simultaneously for enhanced efficacy and specificity.

Helping you overcome the challenges seen in dual binding, antibody screening, tissue tropism, pharmacodynamics, analysis, and overall complexity within the process.

Products and Platforms

Bioproduction

CHOSOURCEプラットフォーム

CHOSOURCE™発現プラットフォームは、安定細胞株の開発において、高レベルで治療用組換えタンパク質を発現するクローンを迅速に作製することを可能にします。

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cellometer-ascend-automatic-cell-counter-512x288.png

Cell Counting & Image Cytometry Instruments

Revvity offers a leading portfolio of automated cell counters, image cytometry systems, and cell counting reagents and consumables. Together, they provide fast, accurate and efficient ways to assess cell health and viability.

Learn more
microplate readers

マイクロプレートリーダー

マイクロプレートリーダーは、マイクロプレート内のサンプルから生物学的・化学的・生化学的、あるいは物理的な反応を検出するための装置です。

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High Content Screening Instruments

ハイコンテントスクリーニング装置

ハイコンテント解析(HCA)またはハイコンテントスクリーニング(HCS)は、ハイスループットの自動イメージングと解析を組み合わせ、シングルセルレベルで定量的なマルチパラメトリックデータを抽出します。

Learn more
microfluidic-protein-characterization-thumbnail-512x288.jpg

マイクロ流体によるタンパク質特性評価

タンパク質は、そのサイズ、分子構造、物理化学的性質が互いに異なります。これらの違いにより、分離と同定によるタンパク質の分析と特性解析が可能になります。

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cell-img

Cellular Imaging Software

Revvityは、より効果的かつ効率的に画像データを取得、可視化、解析、共有するための洗練された細胞イメージングおよび画像解析ソフトウェアを提供しています。

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in-vivo-imaging-512x288.jpg

In vivo イメージング

生物学的プロセスと疾患の進行を追跡、モニタリング、可視化することは、生物学の理解を深めるだけでなく、開発プロセスの早い段階で潜在的な新薬候補の有効性を評価する上で極めて重要です。

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immunoassays

イムノアッセイ

1950年代にイムノアッセイが導入されて以来、イムノアッセイは研究や創薬に不可欠な要素となってきました。

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Featured content

Infographic

Addressing the challenges in modern biotherapeutic development

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Whitepaper

Addressing the challenges of bispecific antibody characterization with high-throughput platforms

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Webinar

Higher throughput bioanalytical methods accelerate the development and evaluation of advanced biotherapeutics

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Application Note

Streamlining the development of bispecific antibodies from expression to quality assessment with Revvity’s biotherapeutic workflow solutions

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Antibody drug conjugates

Revolutionize your therapeutic development with our ADC solutions that can help you discover, develop, and evaluate payload, efficacy and toxicology/safety studies.

Our solutions, including CRISPR tools and screening services, generation of cell models, high-content screening, linker-drug characterization, antibody conjugation, data modelling, potency and detection platforms, and antibody binding and functional assays, can support the precision and reliability required at each stage of your workflow, from discovery through preclinical development.

Products and Platforms

antibody-drug-conjugates-thumbnail-512x288

抗体薬物複合体(ADC)サービス

がん治療薬の探索において、抗体薬物複合体(ADC)は急速に注目を集めており、数百の候補品が臨床開発段階へと進んでいます。

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Bioproduction

CHOSOURCEプラットフォーム

CHOSOURCE™発現プラットフォームは、安定細胞株の開発において、高レベルで治療用組換えタンパク質を発現するクローンを迅速に作製することを可能にします。

Learn more
cellometer-ascend-automatic-cell-counter-512x288.png

Cell Counting & Image Cytometry Instruments

Revvity offers a leading portfolio of automated cell counters, image cytometry systems, and cell counting reagents and consumables. Together, they provide fast, accurate and efficient ways to assess cell health and viability.

Learn more
immunoassays

イムノアッセイ

1950年代にイムノアッセイが導入されて以来、イムノアッセイは研究や創薬に不可欠な要素となってきました。

Learn more
High Content Screening Instruments

ハイコンテントスクリーニング装置

ハイコンテント解析(HCA)またはハイコンテントスクリーニング(HCS)は、ハイスループットの自動イメージングと解析を組み合わせ、シングルセルレベルで定量的なマルチパラメトリックデータを抽出します。

Learn more
microfluidic-protein-characterization-thumbnail-512x288.jpg

マイクロ流体によるタンパク質特性評価

タンパク質は、そのサイズ、分子構造、物理化学的性質が互いに異なります。これらの違いにより、分離と同定によるタンパク質の分析と特性解析が可能になります。

Learn more
signals-box-512x288

Signals

Simplify data capture, processing, and analysis at each ADC development stage, and identify the most promising antibodies, linkers, and payloads.

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pHSense Reagents

pHSense Reagents

Discover a powerful new plate reader tool specifically designed for cell surface target internalization studies for ADC and GPCR research.

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Featured content

Webinar

Antibody drug conjugates: A novel targeted approach to cancer therapy

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Whitepaper

Preclinical screening platforms for antibody-drug conjugate therapeutics

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Technical Note

Revolutionizing ADC development: The critical role of advanced dispensing systems

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RNA vaccines and therapeutics

Enhance your RNA therapeutics and vaccine workflows with solutions that can help you produce a safer and efficient approach. With the right support and expertise benefit from the versatility and ease of adaptability a mRNA or other RNA modality platforms can provide.

We can help in target identification, characterization, assay development for early-stage research and screening, as well as preclinical development workflows including evaluation of immunogenicity to support your modality’s efficacy and safety. Our tools and services can address your RNA payload evaluation, optimization and delivery.

Products and Platforms

microfluidic-nucleic-acid-analysis-thumbnail-512x288.jpg

マイクロ流体核酸分析

従来のゲル分離を簡略化し、わずかな時間でデータの再現性を向上させることができます。LabChip™自動マイクロ流体キャピラリー電気泳動技術を利用した分離では、ゲノムサンプルを数十秒で分析できます。

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lentivirus 512x288

Lentivirus

Lentiviruses are a subtype of retroviruses which have a single stranded RNA genome that encode for three major structural genes: gag, pol, and env.

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aav-thumbnail-512x288

AAV

Our high-quality premade AAV particles are ideal for pilot studies, or as standardized test material for product, process, or assay development.

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rna interference

RNA Interference

Dharmacon™ siRNA, shRNA, and microRNA-based reagents, leading the field for nearly 30 years providing highly specific and efficient gene silencing.

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oligonucleotide custom synthesis

Oligonucleotide Custom Synthesis

Leveraging almost 30 years of experience as a leading provider in oligo design and synthesis, Revvity's oligo synthesis team offers a range of services.

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immunoassays

イムノアッセイ

1950年代にイムノアッセイが導入されて以来、イムノアッセイは研究や創薬に不可欠な要素となってきました。

Learn more
microplate readers

マイクロプレートリーダー

マイクロプレートリーダーは、マイクロプレート内のサンプルから生物学的・化学的・生化学的、あるいは物理的な反応を検出するための装置です。

Learn more

Featured content

Whitepaper

An emerging therapeutic modality - RNA carves its path out of the paradigm

Learn more
Article

Rethinking the vaccine landscape

Learn more
Link

Novel RNA therapeutic modalities

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Webinar

Enabling RNA modalities for therapeutic innovation: Harnessing microfluidic characterization

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Featured resources

Article

Innovative design and engineering approaches driving the next generation of antibody therapeutics

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