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Bioprocessing

Strong foundations, exceptional results.

Bioprocessing is heavily regulated to protect individuals, deliver product quality, and promote ethical practices. Working with trusted partners helps companies meet regulatory standards while optimizing therapeutic potency and scaling process research.

To support your upstream bioprocessing development research, we provide bioanalytical platforms and reagents, plus development partnerships to help you address critical challenges such as quality control, batch consistency, production scale up, regulatory compliance, and development costs.
 

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For research use only. Not for use in diagnostic procedures.

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Mammalian expression systems

Stable cell lines, stronger starts

Stable cell lines, stronger starts

The right expression platform is fundamental to future therapeutic success, creating opportunities to reduce manufacturing costs and ensure consistent product quality. We offer a robust platform for cell line development with our portfolio of expression systems and cell line engineering services, providing the freedom you need to accelerate therapeutics to first-in-human studies.

The CHOSOURCE expression platform contains a well-established GS KO cell line, a glycoengineered ADCC+ cell line, and TnT transposon vector, plus flexible licensing terms, to help streamline development and manufacturing processes.

Custom editing services support specific manufacturing needs for protein and viral vector therapeutics, backed by over 10 years of experience in gene editing for biotherapeutic manufacturing.

Our new beta program supports developers looking to improve vector manufacturability.

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Clone selection and characterization

Reliable accuracy, streamlined workflows

Reliable accuracy, streamlined workflows

Address bottlenecks within clone selection and characterization with regulatory-compliant platforms that reduce resource intensity and provide assay consistency.

Our cell counters and image cytometers can evaluate thousands of clones through automated processes so you can quickly assess cell viability, determine transfection efficiency, monitor growth, identify single colonies, and achieve high-throughput hit selection.

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Quality assurance and quality control

Test with confidence, deliver with trust

Test with confidence, deliver with trust

We offer tools to help you characterize your therapeutic research at every step of the bioprocessing development workflow. Through innovative, robust platforms, reliable and sensitive assays, and reagents produced with strict manufacturing practices, we provide you with confidence in your product.

Identify impurities through our range of host cell contamination detection assays and technologies, evaluate plasmid integrity rapidly with our microfluidics platform, and assess functionality with reduced time and effort using our no-wash AlphaLISATM and HTRFTM assays.

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Scale up and manufacturing

Compliant foundations, consistent results

Compliant foundations, consistent results

When looking to scale up your therapeutic research, turn to our innovative platforms and reagents that can help ensure you transition your workflow as simply and effortlessly as possible.

Our GMP reagents are manufactured under controlled, traceable, and consistent workflows and are fully compliant with regulatory standards. These reagents are supported by strict documentation and released with independent quality oversight. Furthermore, our integrated automation systems have been continuously developed over the last 30+ years to provide you with benefits in throughput, capacity, and format selection, and can help reduce the risk of late-stage setbacks.

Explore our solutions

Bioproduction

CHOSOURCEプラットフォーム

CHOSOURCE™発現プラットフォームは、安定細胞株の開発において、高レベルで治療用組換えタンパク質を発現するクローンを迅速に作製することを可能にします。
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遺伝子改変細胞株作製受託サービス

プロジェクトの進捗は定期的に報告され、最終クローンおよび親株の出荷前には、検証および品質管理(QC)が随時実施されます。最終的には、完全なデータパックとともに納品されます。
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AAV Production Platform

Are you struggling to find a scalable suspension-adapted producer line? Wrestling with problematic payloads? Low production yields? Or a high proportion of empty vectors?
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Cell Counting & Image Cytometry Instruments

Revvity offers a leading portfolio of automated cell counters, image cytometry systems, and cell counting reagents and consumables. Together, they provide fast, accurate and efficient ways to assess cell health and viability.
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microplate readers

マイクロプレートリーダー

Revvityのプレートリーダー製品群は、今日のラボの多様なアッセイ要件に対応する最新の検出技術を備えています。
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Immunoassays solutions

Immunoassays Solutions

From traditional ELISAs to next-gen no-wash and flow-based methods, our solution adapts to your workflow - boosting efficiency, speeding up results, and helping you push the boundaries of discovery.
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pHSense Reagents

pHSense Reagents

Discover a powerful new plate reader tool specifically designed for cell surface target internalization studies for ADC and GPCR research.
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マイクロ流体によるタンパク質特性評価

タンパク質は、そのサイズ、分子構造、物理化学的性質が互いに異なります。これらの違いにより、分離と同定によるタンパク質の分析と特性解析が可能になります。
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Cell-Vive GMP cell culture reagents

Manufactured and tested in accordance with USP Chapter <1043>, Ancillary Materials for Cell, Gene, and Tissue-Engineered Products and Ph. Eur. Chapter 5.2.12 in a dedicated GMP facility compliant with ISO 13485:2016.

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Fontus Workstations

With easy-to-use software, optimized deck access, verified protocols, and reformatting capabilities to simplify your workflows and improve turnaround times
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Janus G3 Liquid Handling Workstation-Revvity

JANUS ワークステーション

JANUS™ G3 自動液体分注ワークステーションは、お客様の特定のアプリケーションニーズに対応する柔軟な自動サンプル準備ソリューションを提供します。
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Workstation Modules

ワークステーションモジュール

カスタムエクスプローラーG3統合ワークステーションは、2種類のモジュールから構成することができます。
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Immune cell targeting in advanced cell and gene therapy research

細胞・遺伝子治療

近年の細胞・遺伝子治療の成功は、次世代の先端治療薬への道を開きました。課題は残るものの、細胞・遺伝子治療研究は、CAR-T、CRISPR、ベクターなどの新しい治療法の開発・提供方法において、変革的な変化を遂げつつあります。
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biologics

バイオロジクス

モノクローナル抗体、リコンビナント・タンパク質、ワクチン、標的を絞った次世代細胞・遺伝子治療など、治療アプローチを強化するために設計された高精度バイオロジクスツールで進歩を遂げましょう。
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GMP Workflows

Supporting your GMP manufacturing workflows in areas of detecting and quantifying harmful impurities to help you produce products with improved reliability and reproducibility.
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Featured products

LabChip GX and GXII Analyzers
LabChip GXII Touch Protein Characterization System
Part number: CLS138160
View details
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Cellaca MX High-throughput Cell Counter
Part number: MX-AOPI
View details
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Celigo Image Cytometer
Part number: 200-BFFL-5C
View details
Cellometer Ascend Automatic Cell Counter
Cellometer Ascend Automated Cell Counter
Part number: CMT-ASD
View details
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Featured resources

Scientific poster

Improved Inter-Instrument Consistency and High Precision for CHO Cell Bioprocessing Using the Cellaca™ MX High-Throughput Cell Counter

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Brochure

Cellaca MX high-throughput cell counter - bioprocessing

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White paper

Maximizing returns in biotherapeutic investment: Financial considerations for expression systems

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Application note

Cellometer Ascend: cell count, viability, and cell-based assays

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Webinar

Higher throughput bioanalytical methods accelerate the development and evaluation of advanced biotherapeutics

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Featured Blogs

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Three productivity advantages of switching to transposon-based integration.

Switch from random integration to transposon-based integration and improve your efficiency, stability, and consistency for faster biotherapeutic production

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CHOSOURCE in action: Powering global tetanus prevention.

Trinomab Therapeutics has partnered with Revvity’s CHOSOURCE expression platform to gain market approval of a first-in-class recombinant anti-tetanus toxin drug.

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How to improve plasmid DNA quality control to accelerate RNA innovation.

Explore how plasmid DNA quality impacts RNA therapeutics and how tools like the LabChip™ enable faster analysis and streamlined workflows

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Precision base editing unlocks new potential for in vivo gene therapies.

Explore how the Pin-point base editing platform can help advance gene therapy in this blog and get the supporting scientific poster.

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Revolutionizing cell therapies with base editing and AI-engineered CRISPR-Cas enzymes.

Discover how base editing and AI-engineered CRISPR-Cas enzymes are revolutionizing cell therapies in this blog.

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Happy birthday Cellometer Ascend – and Q&A with Charles Hernandez.

Happy birthday Cellometer Ascend – and Q&A with Charles Hernandez.

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Happy birthday Cellometer Ascend – and Q&A with Charles Hernandez.

Happy birthday Cellometer Ascend – and Q&A with Charles Hernandez.

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The economic factors shaping expression system decisions and manufacturing strategies.

Explore the financial implications of expression system selection in recombinant protein production. Learn how to optimize costs, timelines, and sustainability for better returns on investment.

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