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  • ホーム
  • Products
  • 研究・開発
  • 研究ソリューション
  • 細胞・遺伝子治療
    • バイオプロセシング
    • Cellular Internalization Kits and Reagents
    • Agrigenomics Workflows
    • アッセイ開発ワークフロー
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    • プレシジョン・メディシン・リサーチ
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  • Cell Therapy Solutions
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  • Accelerating CAR-T Cell Therapy

Accelerating CAR-T Cell Therapy

Scalable solutions, smarter editing, and faster delivery for your next breakthrough in cell therapy

Developing CAR-T therapies requires precision, speed, and scale. Revvity empowers researchers, biopharma innovators, and CDMO/CRO partners with an integrated portfolio of technologies and assays - from high-fidelity genome editing to optimized vector delivery and functional testing.

Whether you're advancing autologous or allogeneic CAR-T programs, our platforms help de-risk development and accelerate time to clinic.

What we offer:

  • Modular gene editing with Pin-point™ base editing platform
  • High-efficiency lentiviral transduction with LentiBOOST™ technology and QA/QC evaluation with microfluidic based CE – LabChip™ system
  • GMP-grade, cell culture and ancillary reagents for ex vivo cell bioprocessing and downstream applications
  • T cell functional assays and detection platforms
  • CRISPR screens
  • Cell counters
  • High-content imaging
Accelerating CAR-T Cell Therapy
  • Quick links
  • Solutions
  • Workflow
  • CGT stages
  • Technologies
  • Resources
  • Get help

Gene editing

From Discovery to Manufacturing 01

Pin-point™ base editing platform

Pin-point™ base editing platform for precise, multiplexed knock-in/knock-out

Learn more
From Discovery to Manufacturing 02

CRISPR editing tools

Revvity Dharmacon™ Edit-R™ CRISPR-Cas9 reagents

Learn more
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Vector delivery

From Discovery to Manufacturing

LentiBOOST™ technology

LentiBOOST™ technology for enhanced lentiviral transduction

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From Discovery to Manufacturing

Lentivirus services

Supporting lentiviral vector development for cell therapies

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Cell processing

From Discovery to Manufacturing 05

Cell processing

BioLegend's Cell-Vive™ GMP portfolio

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Functional assays for T-cell biology

From Discovery to Manufacturing 06

Cytokine assay reagents

A full range of cytokine assay kits in easy-to-use formats.

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From Discovery to Manufacturing 07

Dharmacon™ CRISPR knockout

Dharmacon™ CRISPR knockout, CRISPRi, and CRISPRa tools

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全てを表示 View less

CAR-T solutions

Support for research, process development, and manufacturing.

Base editing

Pin-point™ base editing platform

Pin-point™ base editing platform

Pin-point™ Base Editing Platform: Achieve simultaneous knock-out of multiple genes and targeted CAR knock-in with high editing precision, low off-target effects, and improved cell viability. Modular and scalable, it's ideal for allogeneic CAR-T development.

View details

CRISPR tools

Dharmacon CRISPR tools

CRISPR-Cas9 Editing Tools

Using Revvity's Dharmacon™ Edit-R™ CRISPR-Cas9 reagents, make targeted, specific edits to virtually any gene in any cell type. Pre-edited cell lines and expert genome engineering services are also available.

View details

Transduction Enhancer

LentiBOOST technology

LentiBOOST™ transduction enhancer

Improve lentiviral gene transfer into T cells with higher vector copy number and enhanced CAR expression - without compromising viability or phenotype. Compatible with dual-CAR constructs and hard-to-transduce cells.

View details

Lentivirus manufacturing

Lentiviral vector manufacturing

Lentiviral vector manufacturing

End-to-end support for lentiviral vector development (USP & DSP) optimized for minimal process and product related impurities in research, discovery, or preclinical programs.

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Microfluidic based CE

Microfluidic analysis

Microfluidic analysis

LabChip™ microfluidic capillary electrophoresis (micro-CE) simplifies gel separations, delivering robust data in less time for QC and process monitoring.

View details

Cell counters and cytometry

Cell Counters & Cytometry

Cell counters and cytometry

Automate your workflow with our portfolio of cell counters, image cytometry systems, and related reagents.

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High content imaging

High-Content Imaging

High-content imaging

Generate publication-quality images to accelerate discovery and deepen insight in your CAR-T workflows.

View details

T cell functional assays

T Cell Functional Assays

T cell functional assays

Validate CAR-T activity in vitro with high-throughput assays for T cell proliferation, cytokine profiling, and iTreg suppression. Ideal for IND-enabling studies.

View details

Explore CAR-T applications

De-risk development with fit-for-purpose solutions at every stage

Stage Relevant Solutions
Discovery & lead identification
  • Pin-point™ base editing for target knock-in/knock-out
  • Dharmacon™ CRISPR knockout, knock-in, CRISPRi/a tools
  • Functional genomics screens to validate targets
Therapeutic payload & delivery
  • LentiBOOST™ transduction enhancer
  • Lentiviral vector manufacturing services
  • LabChipTM - microfluidic based CE
Pre-clinical development
  • Cell-Vive™ GMP reagents for ex vivo processing
  • AlphaLISATM and HTRFTM cytokine assay platforms
Scale-up & manufacturing
  • Cell-Vive™ GMP-grade media and cryopreservation solutions
  • Automated, high-throughput compatible assays
Quality assurance & control
  • CRISPR-based functional validation
  • Cell counters

CAR-T enabling technologies

Gene editing & engineering

pin-point base editing platform thumbnail

Pin-point™ 塩基編集プラットフォーム

革新的なPin-point塩基編集サービスにより、複数遺伝子の精密かつ効率的な編集を通じて、治療研究を前進させましょう。

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crispr technologies

CRISPR Technologies

CRISPR-Cas9 genome engineering technologies hold great promise for understanding diseases and for the development of life saving treatments.

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Viral vector delivery

LentiBOOST-TransductionEnhancer512x288

LentiBOOST 形質導入エンハンサー

LentiBOOST™テクノロジーは、さまざまな細胞タイプにおけるレンチウイルスベクターの臨床応用向けに開発された、高い効果を発揮する非細胞毒性の形質導入でエンハンサーです。

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Lentivirus Services

Lentivirus is an efficient tool for fast, efficient, and cost-effective generation of stable homogeneous cell models for strong gene expression or gene knockdown.

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Analytics & quality control

microfluidics-thumbnail.jpg

マイクロ流体分析

タンパク質、核酸、またはその両方を分析する必要がある場合、当社の自動マイクロ流体キャピラリー電気泳動技術は、従来のゲル分離を簡素化し、わずかな時間で確実な分析を実現します。

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Cell Counting & Image Cytometry Instruments

Revvity offers a leading portfolio of automated cell counters, image cytometry systems, and cell counting reagents and consumables. Together, they provide fast, accurate and efficient ways to assess cell health and viability.

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High Content Screening Instruments

ハイコンテントスクリーニング装置

ハイコンテント解析(HCA)またはハイコンテントスクリーニング(HCS)は、ハイスループットの自動イメージングと解析を組み合わせ、シングルセルレベルで定量的なマルチパラメトリックデータを抽出します。

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Reagents & cell culture

Cell-Vive™ GMP-grade ancillary reagents: Serum-free, defined formulations designed for precision, safety, and scalability from R&D through manufacturing.

Advance with Cell-Vive™ GMP solutions

Cell-Vive™ GMP cryopreservation media: Low-DMSO GMP-grade formulation optimized for cryopreserving T cells from various sources while minimizing cytotoxicity.

Explore BioLegend’s cryopreservation media

Functional assays & screening

immune-cell-screening512x288

免疫細胞スクリーニング

標的同定とリード最適化のための生物学的に関連する問題を解決するために、ヒト初代免疫細胞を使用した非臨床スクリーニングサービス

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Explore curated technical content grouped by topic

Base editing & allogeneic CAR-T

White Paper

The Future of Immunotherapy with Base Editing

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Poster

Allogeneic CAR-T Cells by Simultaneous Multiplex Knockout

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Poster

Single Intervention CAR-T Generation Using Multiplex Base Editing

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Poster

Pin-point™ Platform for Allogeneic Cell Therapies with AI-Engineered Cas Enzyme

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Lentiviral delivery - LentiBOOST™ technology

Poster

LentiBOOST™ Transduction Enhancer for T Cell Applications

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White Paper

Transforming Cell Therapies with Dual CAR Strategies

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GMP-grade cell bioprocessing reagents - Cell-Vive™ GMP portfolio

Webinar

GMP Manufacturing of Ancillary Reagents

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Webinar

T Cell Therapy Workflow

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Infographic

CAR-T Research and Development Workflow Solutions

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Infographic

End-to-End Solutions for T Cell Bioprocessing

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T cell exhaustion & epigenetic screening

White Paper

Epigenetics and CRISPR Screens in T Cell Exhaustion

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For research use only. Not for use in diagnostic procedures.

Pin-point™ Reagents & Platform: Pin-point™ base editing reagents are available for research use only and are not for diagnostic use or direct administration into humans or animals. The Pin-point™ base editing platform technology is available for clinical or diagnostic study and commercialization under a commercial license from Revvity.

LentiBOOST™ Pharma-Grade: For research use only. Not for use in diagnostic procedures.

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