Enabling immunogenicity and pharmacological studies of biotherapeutic drugs
The immunogenic potential of biotherapeutic drug molecules can have an effect at any point, from its administration through to metabolism and elimination. Therefore, it is important to understand the impact of immunogenicity upon the pharmacokinetic (PK) and pharmacodynamic (PD) properties of a large molecule drug.
The characterization of the effect of anti-drug antibodies on the PK is critical. The development of a physiologically relevant PK model in the context of the immunogenicity profile offers significant value to preclinical development.
We offer technology platforms that enable in vitro, ex vivo, and in vivo evaluations to help you understand the immunogenicity of your biologics.
For research use only. Not for use in diagnostic procedures.
