An integrated innovation and production hub advancing viral vector design, engineering, and manufacturing to support developers from early discovery through scalable process development.
A commercial license is required for any clinical or commercial application involving AAVs developed using Revvity technologies.
Summary
- Expertise across AAV and lentiviral delivery systems
- Integrated technologies for engineering, manufacturing, and analytics
- End-to-end support from vector design to process development
- Scientific collaboration beyond traditional service
Viral vector partners who bring the science, not just the service.
Viral vector development demands both scientific integrity and strategic foresight.
As programs advance toward the clinic, teams face growing pressure to optimize vector performance, ensure scalability, and reduce risk, often within compressed timelines. Decisions made early in development can have significant long-term impact, yet many teams lack access to the right integrated scientific support when they need it most.
Success in this environment requires more than traditional vendor relationships.
What's needed is a partner that can contribute not just tools, but insight, helping anticipate challenges, support your design decisions, and streamline the path to scalable processes.
A hub of expertise. Working as your team.
The Viral Vector Center of Excellence goes beyond being just a site.
The Center is a connected scientific hub bringing together expertise in vector design, engineering, development, and enabling technologies, built to support viral vector programs as they evolve.
This model reflects a shift from transactional support to integrated scientific partnership.
Here, development is approached not as disconnected steps, but as a continuous, aligned process where early decisions, engineering strategies, and process considerations are aligned from the start.
Core capabilities
Viral vector center of excellence capabilities:
- Tropism
- Payload expression
- Manufacturing
- Analytics
AAV technologies and services
Viral Vector Tropism
Technology:
- Custom AAV capsid development
- Validated capsids for retina, CNS, and bone tissue applications
Services:
- Capsid library manufacturing for directed evolution and rational design
- Non-human primate studies for capsid validation
Technology:
- Custom AAV capsid development
- Validated capsids for retina, CNS, and bone tissue applications
Services:
- Capsid library manufacturing for directed evolution and rational design
- Non-human primate studies for capsid validation
Payload Expression
Technology:
- Tissue-specific promoters through third parties
Services:
- Payload expression cassette engineering: single vectors and libraries
- Payload expression cassette screening: in vitro and in vivo evaluation
Technology:
- Tissue-specific promoters through third parties
Services:
- Payload expression cassette engineering: single vectors and libraries
- Payload expression cassette screening: in vitro and in vivo evaluation
Viral Vector Manufacturing
Technology:
- Optimized transfer plasmid backbones and packaging plasmids
- Payload suppression for vector production: Vectonize™
Services:
- Gene therapy manufacturing: discovery through early preclinical phases, including novel capsid production and purification process development
- Technology and reagent validation: upstream/downstream proof-of-concept services for hire
Technology:
- Optimized transfer plasmid backbones and packaging plasmids
- Payload suppression for vector production: Vectonize™
Services:
- Gene therapy manufacturing: discovery through early preclinical phases, including novel capsid production and purification process development
- Technology and reagent validation: upstream/downstream proof-of-concept services for hire
Viral Vector Analytics
Reagents:
- AAV reference standards for QC calibration and assay validation
Services:
- AAV analytical testing: Standard and custom-developed assays
Reagents:
- AAV reference standards for QC calibration and assay validation
Services:
- AAV analytical testing: Standard and custom-developed assays
LV technologies and services
Viral Vector Tropism
Technology:
- Modular surface modification platform for targeted lentiviral vectors
Services:
- Custom manufacturing workflows for unique pseudotype configurations and non-conventional vector designs
Technology:
- Modular surface modification platform for targeted lentiviral vectors
Services:
- Custom manufacturing workflows for unique pseudotype configurations and non-conventional vector designs
Payload Expression
Technology:
- LentiBOOST™ transduction enhancer technology for discovery up to clinical applications
- Cell-specific promoters through third parties
Services:
- Custom library design, e.g., CAR and TCR
- In vitro CAR‑T functional characterization: expression, activation, cytotoxicity
Technology:
- LentiBOOST™ transduction enhancer technology for discovery up to clinical applications
- Cell-specific promoters through third parties
Services:
- Custom library design, e.g., CAR and TCR
- In vitro CAR‑T functional characterization: expression, activation, cytotoxicity
Viral Vector Manufacturing
Technology:
- Optimized transfer plasmid backbones to improve manufacturability
Services:
- Flexible scale-up capabilities for both adherent and suspension cell systems
- Project-tailored vector purification and processing for early-stage research programs and preclinical studies
Technology:
- Optimized transfer plasmid backbones to improve manufacturability
Services:
- Flexible scale-up capabilities for both adherent and suspension cell systems
- Project-tailored vector purification and processing for early-stage research programs and preclinical studies
Viral Vector Manufacturing
Services:
- LV analytical and functional characterization: Standard and custom-developed assays
Services:
- LV analytical and functional characterization: Standard and custom-developed assays
What makes this different
| Traditional approach | Viral vector center of excellence |
|---|---|
| Manufacturing provider | Scientific innovation hub |
| Transactional relationship | Collaborative partnership |
| Fragmented services | Integrated platform |
| Execution-focused | Guidance-driven development |
Expertise that strengthens every stage of development
We support viral vector programs as they evolve across the full development journey:
- Early vector design and feasibility
- Engineering and optimization
- Process development
- Scale-up readiness
- Ongoing scientific collaboration and problem-solving
The goal is simple: reduce friction between stages and help teams move forward with confidence.
Why Munich
Munich is more than a location, it is a concentration of expertise.
Leveraging decades of experience in viral vector engineering and manufacturing, incorporating the expertise of SIRION Biotech within Revvity Viral vector center of excellence, the site brings together strong foundations in both AAV and lentiviral systems, supported by advanced engineering platforms and enabling technologies.
This combination creates an environment where scientific depth and operational capability intersect, supporting more informed development decisions and more efficient program progression.
Enabling solutions
