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  • Cutting NGS costs without cutting science.
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Blog

NGS NGS Library Prep

Apr 8th 2025

1 min read

Cutting NGS costs without cutting science.

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In response to recent NIH funding pauses and shifting federal regulation, research institutions are seeking cost-effective solutions that maintain the integrity of their scientific endeavors. Revvity is committed to supporting the research community by offering high-quality, affordable accessory products compatible designed to reduce lab’s costs with various NGS library preparation workflows.

Barcoded Adapters

NEXTFLEX™ barcoded adapters incorporate unique dual indexes (UDI) enable multiplexing of up to 1,536 samples, significantly reducing per-sample sequencing costs and are compatible with Illumina, Watchmaker, Twist, and other TruSeq® style library prep kits. Incorporating full-length UDI and unique molecular identifiers (UMI) via ligation minimizes errors, enhancing data accuracy.

Universal Blockers

Designed to optimize hybridization-based target capture, the NEXTFLEX universal blockers NEXTFLEX Universal Blockers Discover  prevent concatemerization of library molecules, improving the number of on-target reads. They are effective regardless of index length or the presence of a UMI and are compatible with both ligation and tagmentation-based workflows for Illumina and Element sequencing platforms. Notably, these blockers are offered at a fraction of the cost of major competitors, providing a cost-effective solution without compromising performance.

NEXTFLEX NGS Cleanup Beads

The NEXTFLEX NGS Cleanup Beads NEXTFLEX NGS Cleanup Beads Discover  utilize Solid-phase reversible immobilization (SPRI) technology to efficiently purify nucleic acids by removing unwanted components such as primers, salts, and adapters. They selectively bind DNA by size, ensuring high recovery and consistent results. Compatible with both manual and automated workflows, these beads offer a cost-effective alternative to other market leaders, enabling researchers to maintain high-quality results while reducing expenses.

Sustaining Scientific Excellence on a Budget

By integrating NEXTFLEX accessory products into your workflows, you can achieve substantial cost savings—up to 50% with NEXTFLEX cleanup beads and 10-15 times with NEXTFLEX blockers—without sacrificing the quality and reliability of your research outcomes. Our products are designed for seamless compatibility with various library prep protocols, adding flexibility and efficiency to your sequencing projects.

Revvity remains dedicated to empowering researchers with innovative tools that uphold scientific excellence, even in the face of financial constraints.

For research use only. Not for use in diagnostic procedures.

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