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IVISense Folate Receptor 680 Fluorescent Probe (FolateRSense 680)
IVISense Folate Receptor 680 Fluorescent Probe (FolateRSense 680)
IVISense™ fluorescent imaging probes - optimized and validated on Revvity's IVIS® optical imaging platform
| Feature | Specification |
|---|---|
| Unit Size | 1 vial (10 doses) |
| Specificity | Folate receptor |
Product variant
Wave Length: 680 nm
Part #:
NEV10040
For research use only. Not for use in diagnostic procedures.
IVISense Folate Receptor 680 Fluorescent Probe (FolateRSense 680)
IVISense™ fluorescent imaging probes - optimized and validated on Revvity's IVIS® optical imaging platform
IVISense Folate Receptor 680 Fluorescent Probe (FolateRSense 680)
Product information
Overview
Folate receptors are a family of cell surface receptors that bind the essential vitamin folic acid (folate, vitamin B9). These receptors are upregulated in highly metabolic cells and over-expression of FRA protein is associated with tumor growth, as uptake of folic acid is a necessary part of tumor metabolism.
Folate is essential for cellular metabolism and DNA synthesis, methylation, and repair. High metabolic cells such as proliferating cancer cells have increased demand for folate to maintain their accelerated DNA synthesis; thus overexpression of folate receptors (FRs) is a recognized biomarker of many tumors, though tumors can differ in their dependence on folate metabolism.
Specifications
| Brand |
IVISense
|
|---|---|
| Fluorescent Agent Type |
Targeted
|
| Imaging Modality |
Fluorescence
|
| Shipping Conditions |
Shipped Ambient
|
| Specificity |
Folate receptor
|
| Storage Conditions |
+2 to +8 °C
|
| Therapeutic Area |
Arthritis
Cardiovascular
Inflammation
Oncology
Pulmonary
|
| Unit Size |
1 vial (10 doses)
|
| Wave Length |
680 nm
|
Resources
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Whitepaper
Understanding the ‘how’ and ‘why’ of spectral unmixing
In vivo fluorescence imaging displays a very broad utility and has become a well-established modality for functional imaging in...
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