Feature | Specification |
---|---|
Unit Size | 1 vial (10 doses) |
Specificity | Folate receptor |
Folate receptors are a family of cell surface receptors that bind the essential vitamin folic acid (folate, vitamin B9). These receptors are upregulated in highly metabolic cells and over-expression of FRA protein is associated with tumor growth, as uptake of folic acid is a necessary part of tumor metabolism.
Folate is essential for cellular metabolism and DNA synthesis, methylation, and repair. High metabolic cells such as proliferating cancer cells have increased demand for folate to maintain their accelerated DNA synthesis; thus overexpression of folate receptors (FRs) is a recognized biomarker of many tumors, though tumors can differ in their dependence on folate metabolism.
Brand |
IVISense
|
---|---|
Fluorescent Agent Type |
Targeted
|
Imaging Modality |
Fluorescence
|
Shipping Conditions |
Shipped Ambient
|
Specificity |
Folate receptor
|
Storage Conditions |
+2 to +8 °C
|
Therapeutic Area |
Arthritis
Cardiovascular
Inflammation
Oncology
Pulmonary
|
Unit Size |
1 vial (10 doses)
|
Wave Length |
680 nm
|
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