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  • N-succinimidyl-3-(4-hydroxy-3-[125I]iodophenyl)propionate, Bolton-Hunter Reagent, 250 µCi

N-succinimidyl-3-(4-hydroxy-3-[125I]iodophenyl)propionate, Bolton-Hunter Reagent, 250 µCi

NENSure radiochemical vial and container
N-succinimidyl-3-(4-hydroxy-3-[125I]iodophenyl)propionate, Bolton-Hunter Reagent, 250 µCi
NENSure radiochemical vial and container
NENSure™ radiochemical vial and container
NENSure radiochemical vial and container

Bolton-Hunter reagent, monoiodinated. This product is used to iodinate proteins that do not contain tyrosine residues. Bolton-Hunter reagent is the N-hydroxysuccinimide ester of iodinated p-hydroxyphenylpropionic acid. The active ester acylates terminal amino groups with the iodinated p-hydxyphenylpropionic residue, effectively introducing radioactive iodine into proteins and peptides. A non-oxidative technique, it is less harsh to proteins than alternative labeling methods. An anhydrous benzene A charcoal trap is provided with each vial.

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Feature Specification
Fresh Lot Days Fresh upon request
Label Position Nominally Labeled
Molecular Weight 387.2

Bolton-Hunter reagent, monoiodinated. This product is used to iodinate proteins that do not contain tyrosine residues. Bolton-Hunter reagent is the N-hydroxysuccinimide ester of iodinated p-hydroxyphenylpropionic acid. The active ester acylates terminal amino groups with the iodinated p-hydxyphenylpropionic residue, effectively introducing radioactive iodine into proteins and peptides. A non-oxidative technique, it is less harsh to proteins than alternative labeling methods. An anhydrous benzene A charcoal trap is provided with each vial.

View product information
Product variants
Unit Size: 250 µCi
Part #:
NEX120250UC
Unit Size: 1 mCi
Part #:
NEX120001MC
Unit Size: 2 mCi
Part #:
NEX120002MC
For research use only. Not for use in diagnostic procedures.
Request more information
NENSure radiochemical vial and container
N-succinimidyl-3-(4-hydroxy-3-[125I]iodophenyl)propionate, Bolton-Hunter Reagent, 250 µCi
NENSure radiochemical vial and container
NENSure™ radiochemical vial and container
N-succinimidyl-3-(4-hydroxy-3-[125I]iodophenyl)propionate, Bolton-Hunter Reagent, 250 µCi
NENSure radiochemical vial and container
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Product information

  • Overview
  • Specifications

Overview

Iodination of proteins is a common method of adding a tracer with high specific activity to your protein of interest. Bolton-Hunter reagent is the N-hydroxysuccinimide ester of iodinated p-hydroxyphenylpropionic acid. The active ester acylates terminal amino groups with the iodinated p-hydxyphenylpropionic residue, effectively introducing radioactive iodine into proteins and peptides. A non-oxidative technique, it is less harsh to proteins than alternative methods. Bolton-Hunter reagent can be used to label peptides and proteins containing lysine residues. Available in 250 µCi size.

Specifications

Molecular Weight
387.2
Specific Activity
2200 Ci/mmol (81.4 TBq/mmol)
CAS Number
34071-95-9
Application
Drug Discovery & Development
Brand
NEN Radiochemicals
Buffer/Solvent
Anhydrous 2-methyltetrahydrofuran with 250 ppm BHT (butylated hydroxytoluene) stabilizer
Detection Modality
Radiometric
Fresh Lot Days
Fresh upon request
Label Position
Nominally Labeled
Molecular Formula
C13H11I2NO5
Packaging
NENSure vial
Radioisotope
125I
Shipping Information
Shipped Ambient
Shipping Conditions
Shipped Ambient
Special Ordering Information
This is a radioactive product - shipping address must have a license to receive radioactive materials.
Storage Conditions
Ambient or lower
Unit Size
250 µCi

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