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PhenoVue Anti-PARP1 - Mouse IgG2a Antibody
PhenoVue Anti-PARP1 - Mouse IgG2a Antibody
Representative images and quantification of PARP1 expression in HeLa cells treated with vehicle control or SK-575 PROTAC (100 nM, 24 h). Cells were stained with PhenoVue mouse IgG2a anti-PARP1 antibody and detected using PhenoVue Fluor 647 secondary antibody.
The PhenoVue™ anti-PARP1 mouse IgG2a antibody supports imaging and high-content analysis workflows. It is compatible with PhenoVue Fluor goat anti-mouse highly cross-adsorbed antibodies for multiplex fluorescent detection.
| Feature | Specification |
|---|---|
| Quantity | 1 |
The PhenoVue™ anti-PARP1 mouse IgG2a antibody supports imaging and high-content analysis workflows. It is compatible with PhenoVue Fluor goat anti-mouse highly cross-adsorbed antibodies for multiplex fluorescent detection.
Product variant
Unit Size: 100 µL
Part #:
PAMSPARP11
For research use only. Not for use in diagnostic procedures.
PhenoVue Anti-PARP1 - Mouse IgG2a Antibody
Representative images and quantification of PARP1 expression in HeLa cells treated with vehicle control or SK-575 PROTAC (100 nM, 24 h). Cells were stained with PhenoVue mouse IgG2a anti-PARP1 antibody and detected using PhenoVue Fluor 647 secondary antibody.
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Product information
Overview
PARP1 (Poly (ADP-ribose) Polymerase 1) is a key nuclear enzyme that senses single-strand breaks and other DNA lesions. Upon recruitment to sites of damage, PARP1 catalyzes PARylation, recruits DNA repair factors, and remodels chromatin to facilitate repair.
The PhenoVue anti-PARP1 mouse IgG2a antibody can be used in imaging and high-content analysis workflows in the study of cellular responses to DNA damage.
View our validation data in the Product Information Sheet within the Resources tab below.
Specifications
| Form |
Liquid
|
|---|
| Application |
High Content Imaging
Microscopy
|
|---|---|
| Assay Points |
2 x 96-well or 1 x 384-well microplates
|
| Brand |
PhenoVue™
|
| Detection Modality |
Fluorescence
|
| Host Species |
Mouse
|
| Product Group |
Antibody
|
| Quantity |
1
|
| Sample Type |
Fixed cells only
|
| Shipping Conditions |
Shipped in Dry Ice
|
| Storage Conditions |
-16° C or below, protected from light
|
| Target Species |
Human
|
| Type |
Individual reagent
|
| Unit Size |
100 µL
|
Resources
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