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NEXTFLEX blood miRNA blockers
NEXTFLEX blood miRNA blockers
NEXTFLEX NGS Library Prep
| Feature | Specification |
|---|---|
| Automation Compatible | Yes |
| Product Group | Small RNA Accessory |
Product variant
Unit Size: 96 rxns
Part #:
NOVA-513103
For research use only. Not for use in diagnostic procedures.
NEXTFLEX blood miRNA blockers
NEXTFLEX NGS Library Prep
NEXTFLEX blood miRNA blockers
Product information
Overview
Maximize miRNA mapped reads with NEXTFLEX blood miRNA blockers.
The NEXTFLEX blood miRNA blockers deplete common miRNA in whole blood and plasma such as hsa-miR-451a, hsa-miR-486-5p and hsa-miR-92a-3p. These constitute 50-70% of the small RNA present in those samples and usually are not of interest for researchers. They are designed to maximize miRNA mapped reads when using the NEXTFLEX® Small RNA-Seq Kit v4.
Additional product information
Figure 1. NEXTFLEX blood miRNA blockers effectively remove the appearance of three of the most abundant miRNAs appearing in human blood and plasma.
Specifications
| Automation Compatible |
Yes
|
|---|---|
| Product Group |
Small RNA Accessory
|
| Shipping Conditions |
Shipped in Dry Ice
|
| Unit Size |
96 rxns
|
Citations
- Juzenas S, et al (2020). Depletion of erythropoietic miR-486-5p and miR-451a improves detectability of rare microRNAs in peripheral blood-derived small RNA sequencing libraries. NAR Genom Bioinform. 2(1):lqaa008. doi: 10.1093/nargab/lqaa008.
- LaBelle J, et al (2021). Commercially Available Blocking Oligonucleotides Effectively Suppress Unwanted Hemolysis-Related miRNAs in a Large Whole-Blood RNA Cohort. J Mol Diagn.23(6):671-682. doi: 10.1016/j.jmoldx.2021.03.006.
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