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  • Neurotensin, [125I]Tyr3, 50µCi

Neurotensin, [125I]Tyr3, 50µCi

NENSure radiochemical vial and container
Neurotensin, [125I]Tyr3, 50µCi
NENSure radiochemical vial and container
NENSure™ radiochemical vial and container
NENSure radiochemical vial and container

Neurotensin, labeled with 125I on the tyrosine 3 residue. Neurotensin functions as an agonist at neurotensin receptors. It is known to induce analgesia, hypothermia and increased locomotor activity. Neurotensin is also involved in the regulation of dopamine.

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Feature Specification
Fresh Lot Days Third Monday of each month
Label Position Nominally Labeled
Molecular Weight ~1797
Receptor Neurotensin

Neurotensin, labeled with 125I on the tyrosine 3 residue. Neurotensin functions as an agonist at neurotensin receptors. It is known to induce analgesia, hypothermia and increased locomotor activity. Neurotensin is also involved in the regulation of dopamine.

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Product variants
Unit Size: 10 µCi
Part #:
NEX198010UC
Unit Size: 50 µCi
Part #:
NEX198050UC
For research use only. Not for use in diagnostic procedures.
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NENSure radiochemical vial and container
Neurotensin, [125I]Tyr3, 50µCi
NENSure radiochemical vial and container
NENSure™ radiochemical vial and container
Neurotensin, [125I]Tyr3, 50µCi
NENSure radiochemical vial and container
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Product information

  • Overview
  • Specifications

Overview

50 µCi Quantities of Neurotensin, [125I]Tyr3are available for your research.

We offer radioligands and radiolabeled biomolecules to use as tracers, for radioimmunoassays (RIAs), for autoradiographic visualization, or for performing saturation and competition radioligand binding assays to determine receptor expression levels (Bmax), dissociation constants (Kd), association and dissociation rates (kon and koff), and inhibitor constants (Ki) for a variety of receptors. We develop our radioligands to the highest specific activity possible and provide high purity resulting in low non-specific binding products. Each of our ultra-pure radiolabeled compounds is fully characterized for pharmacological action and validated in binding assays.

Radiochemicals remain the most sensitive method for probing binding biology; yielding unprecedented sensitivity gives results that technicians and scientists can trust. For over 50 years, Revvity has been a leading supplier of New England Nuclear (NEN) radiochemicals, liquid scintillation cocktails, vials and nuclear counting detection instruments.

References for NEX198:

  1. Pettibone, D.J., Hess, J.F., Hey, P.J., Jacobson, M.A., Leviten, M., Lis, E.V., Mallorga, P.J., Pascarella, D.M., Snyder, M.A., Williams, J.B., Zeng, Z. (2003), The effects of deleting the mouse neurotensin receptor NTR1 on central and peripheral responses to neurotensin., J Pharmacol Exp Ther, 300 (1): 305-313.

Specifications

Molecular Weight
~1797
Specific Activity
2200 Ci/mmol (81.4 TBq/mmol)
CAS Number
39379-15-2
Application
Drug Discovery & Development
Brand
NEN Radiochemicals
Buffer/Solvent
0.1M potassium phosphate, pH 4.7 : methanol (58:42)
Detection Modality
Radiometric
Fresh Lot Days
Third Monday of each month
Label Position
Nominally Labeled
Molecular Formula
C78H121N21O20
Packaging
NENSure vial
Radioisotope
125I
Receptor
Neurotensin
Shipping Information
Shipped Ambient
Shipping Conditions
Shipped Ambient
Special Ordering Information
This is a radioactive product - shipping address must have a license to receive radioactive materials.
Storage Conditions
-20°C
Therapeutic Area
CNS & Neurologic
Inflammation
Pain
Unit Size
50 µCi

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