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IVISense Renin 680 FAST Fluorscent Probe (ReninSense)

IVISense™ Renin 680 FAST (ReninSense™) is recognized and activated by rodent forms of renin in preclinical in vivo imaging models. IVISense Renin 680 FAST may be used to monitor abnormal Renin-Angiotensin System (RAS) function, progression of disease, and the efficacy of therapeutic treatment in disorders such as hypertension, cardiovascular disease, as well as some neurological diseases.

For research use only. Not for use in diagnostic procedures.

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Feature	Specification
Unit Size	1 vial (10 doses)
Specificity	Renin protease

For research use only. Not for use in diagnostic procedures.

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Product variant

Wave Length: 680 nm

Part #:

NEV11079

For research use only. Not for use in diagnostic procedures.

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Product information

Overview

IVISense Renin 680 FAST™ is a member of a family of activatable fluorescent imaging probes comprising a novel architecture, termed F.A.S.T. (Fluorescent Activatable Sensor Technology), that confers an improved pharmacokinetic profile with a broader range of early imaging timepoints. This architecture also offers higher target specific signal with reduced background.

IVISense Renin 680 FAST is a Renin activatable agent that is optically silent upon injection and produces fluorescent signal after cleavage by renin produced in the kidneys. The Renin-Angiotensin System (RAS) is the hormone system involved in regulating blood pressure and fluid balance in the body.

Specifications

Other specifications

Brand	IVISense
Fluorescent Agent Type	Enzyme activated
Imaging Modality	Fluorescence
Shipping Conditions	Shipped in Blue Ice
Specificity	Renin protease
Storage Conditions	-30 to -16 °C
Therapeutic Area	Hypertension Kidney function
Unit Size	1 vial (10 doses)
Wave Length	680 nm