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  • プラットフォームと自動化
  • イメージング
  • In vivo イメージング
  • In Vivo Imaging Reagents
  • IVISense Fluorescent Probes
  • IVISense Hypoxia CA IX 680 Fluorescent Probe (HypoxySense)

IVISense Hypoxia CA IX 680 Fluorescent Probe (HypoxySense)

IVISense™ fluorescent imaging probes
IVISense Hypoxia CA IX 680 Fluorescent Probe (HypoxySense)
IVISense™ fluorescent imaging probes
IVISense™ fluorescent imaging probes - optimized and validated on Revvity's IVIS® optical imaging platform
IVISense™ fluorescent imaging probes

IVISense™ Hypoxia CA IX 680 (HypoxiSense™ 680) is a carbonic anhydrase IX (CA IX) targeted fluorescent in vivo imaging probe that can be used to image CA IX overexpression in response to hypoxia. Oxygen deprivation is associated with several disease states including angiogenisis, pulmonary disease, inflammation, and cancer.

For research use only. Not for use in diagnostic procedures.

View product information
Feature Specification
Unit Size 1 vial (10 doses)
Specificity Carbonic Anhydrase IX

IVISense™ Hypoxia CA IX 680 (HypoxiSense™ 680) is a carbonic anhydrase IX (CA IX) targeted fluorescent in vivo imaging probe that can be used to image CA IX overexpression in response to hypoxia. Oxygen deprivation is associated with several disease states including angiogenisis, pulmonary disease, inflammation, and cancer.

For research use only. Not for use in diagnostic procedures.

View product information
Product variant
Wave Length: 680 nm
Part #:
NEV11070
For research use only. Not for use in diagnostic procedures.
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IVISense™ fluorescent imaging probes
IVISense Hypoxia CA IX 680 Fluorescent Probe (HypoxySense)
IVISense™ fluorescent imaging probes
IVISense™ fluorescent imaging probes - optimized and validated on Revvity's IVIS® optical imaging platform
IVISense Hypoxia CA IX 680 Fluorescent Probe (HypoxySense)
IVISense™ fluorescent imaging probes
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Product information

  • Overview
  • Specifications

Overview

In cancer, hypoxia occurs in tumors as a result of the poor ability of their disorganized vascular networks to deliver blood borne oxygen. IVISense Hypoxia CA IX 680 fluorescent imaging probe detects the tumor cell surface expression of carbonic anhydrase 9 (CA IX) protein, which increases in hypoxic regions within many tumors, especially in cervical, colorectal, non-small cell lung tumors. Pairing IVISense Hypoxia CA IX 680 agent with optical fluorescent imaging technology allows you to image and quantitate tumor sub-regions undergoing hypoxia-related changes, non-invasively and in vivo.

Specifications

Brand
IVISense
Fluorescent Agent Type
Targeted
Imaging Modality
Fluorescence
Shipping Conditions
Shipped in Blue Ice
Specificity
Carbonic Anhydrase IX
Storage Conditions
+2 to +8 °C
Therapeutic Area
Angiogenesis
Arthritis
Oncology
Unit Size
1 vial (10 doses)
Wave Length
680 nm

Resources

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1-6 of 7 Resources
Flyer Icon
Flyer
Best practices for designing an effective in vivo fluorescence imaging study

Fluorescence molecular imaging is the visualization of cellular and biological function in vivo to gain deeper insights into...

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Application Brief Icon
Application Brief
Characterization of NIR fluorophores for their potential in non-specific tissue accumulation
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eBook Icon
eBook
In vivo imaging solutions

Researchers trust our in vivo imaging solutions to give them reliable, calibrated data that reveals pathway characterization and...

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Guide Icon
Guide
IVISense fluorescent probe selector guide for oncology research

The goal of in vivo fluorescence molecular imaging is to enable non-invasive visualization and quantification of cellular and...

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Application Note Icon
Application Note
Quantitative analysis of 3D microtissue growth and biomarker intensity
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Protocol/SOP
Protocol/SOP
SOP: IVISense Hypoxia CA IX 680 (NEV11070) for in vivo imaging
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