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IVISense Bombesin Receptor 680 Fluorescent Probe (BombesinRSense)
IVISense Bombesin Receptor 680 Fluorescent Probe (BombesinRSense)
IVISense™ fluorescent imaging probes - optimized and validated on Revvity's IVIS® optical imaging platform
| Feature | Specification |
|---|---|
| Unit Size | 1 vial (10 doses) |
| Specificity | Bombesin receptor |
Product variant
Wave Length: 680 nm
Part #:
NEV10090
For research use only. Not for use in diagnostic procedures.
IVISense Bombesin Receptor 680 Fluorescent Probe (BombesinRSense)
IVISense™ fluorescent imaging probes - optimized and validated on Revvity's IVIS® optical imaging platform
IVISense Bombesin Receptor 680 Fluorescent Probe (BombesinRSense)
Product information
Overview
IVISense Bombesin Receptor 680 fluorescent probe is specific for bombesin receptors (BBRs) expressed in many types of cancer. Bombesin-like peptides and their G-protein coupled receptors have been shown to play a role in cancer and are overexpressed in a variety of tumors, including prostate, breast, lung, CNS, gastric, colon, and renal cell carcinomas.
IVISense Bombesin Receptor 680 imaging agent comprises a 7-amino acid bombesin peptide analog, an NIR fluorophore (ex/em 665/691 nm) and a pharmacokinetic modifier to improve its plasma availability (plasma t1/2 = 30-45 min). This agent can be used to target and quantify upregulation of bombesin receptors (BBR) in vivo associated with tumor proliferation.
Specifications
| Brand |
IVISense
|
|---|---|
| Fluorescent Agent Type |
Targeted
|
| Imaging Modality |
Fluorescence
|
| Shipping Conditions |
Shipped Ambient
|
| Specificity |
Bombesin receptor
|
| Storage Conditions |
+2 to +8 °C
|
| Therapeutic Area |
Oncology
|
| Unit Size |
1 vial (10 doses)
|
| Wave Length |
680 nm
|
Resources
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Application Note
Development of a near infrared fluorescent labeled agent for assessing bombesin receptor expression in cancer
Application Note
Multiplex 2D imaging of NIR molecular imaging agents on the IVIS SpectrumCT platform
Epifluorescence (2D) imaging of superficially implanted mouse tumor xenograft models offers a fast and simple method for assessing...
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