IVISense 645 NHS Fluorescent Dye (5 mg) (VivoTag)

IVISense 645 NHS fluorescent dye is an amine-reactive near-infrared (NIR) fluorochrome for coupling via a NHS ester linkage to peptides, small molecules, proteins, antibodies or macromolecules. Unit size 5 mg.

IVISense™ 645 fluorescent dyes are ideal for molecular labeling for use in preclinical in vivo imaging applications and in vitro corroboration assessments by microscopy and flow cytometry. IVISense 645 dyes are well suited for the labeling and imaging of proteins, antibodies, and small molecules in a wide range of research areas. The 645 nm fluorescence wavelength is ideal for biological imaging applications using in vivo fluorescence systems and advanced microscopes, high content imaging and flow cytometry.

• Uniquely optimized for the generation of in vivo imaging probes with low non-specific accumulation at tumor sites and inflammatory sites.
• Aligned with light sources and filters in all commonly used microscopes, flow cytometers, and plate readers.
• Suitable for in vivo multiplexing with 750 or 800 nm Revvity probes or other labeled proteins/Abs.  Expanded in vivo multiplexing using the IVIS™ platform spectral unmixing with 680/750/800 nm probes or antibodies.
• Requires maintaining mice on alfalfa-free diet to remove spectral overlap with diet autofluorescence.
• Recommended dye:protein ratio of 1-3.