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Membrane Target Systems: GABA B1b (human) membrane preparation, in CHO-K1 cells. 400 Units.
Membrane Target Systems: GABA B1b (human) membrane preparation, in CHO-K1 cells. 400 Units.
Receptor cell membranes
| Feature | Specification |
|---|---|
| µg protein/unit | 4 µg protein / unit |
| Concentration | 4 µg/µL protein |
| G-Alpha Natural Receptor | Gi/Go |
| Host Cell Line | CHO-K1 |
| Host Species | Human |
| Receptor | GABA |
| Target Class | GPCR |
| Validation | Binding |
| Volume | 400.0 µL |
Product variant
Unit Size: 400 units
Part #:
6110546400UA
For research use only. Not for use in diagnostic procedures.
Membrane Target Systems: GABA B1b (human) membrane preparation, in CHO-K1 cells. 400 Units.
Receptor cell membranes
Membrane Target Systems: GABA B1b (human) membrane preparation, in CHO-K1 cells. 400 Units.
Product information
Overview
Membrane Target Systems are quality assured frozen membranes from cells that express GABA B1b (human) recombinant or endogenous receptors.
We submit every batch of receptor to stringent quality control testing that includes saturation radioligand binding assay to determine receptor concentration (Bmax) and affinity (Kd). Competition binding assays are performed determine affinity (Ki) against known reference agonists and antagonists. GTP?S data is also provided for some of our Gi-coupled receptors.
Membranes are carefully prepared and ready for a variety of HTS applications, including radioligand binding (using either proximitymethods, such as FlashPlate, or classical filtration methods).
Products are packaged as frozen crude membrane preparations. One assay unit is defined as micrograms of protein, defined by competition binding assay (filtration). A complete product description and recommended protocol are included on the Product Information Sheet.
Some of our receptors may be restricted for sale in specified countries. Please inquire.
Specifications
| Concentration |
4 µg/µL protein
|
|---|---|
| Volume |
400.0 µL
|
| µg protein/unit |
4 µg protein / unit
|
| Application |
Drug Discovery & Development
|
|---|---|
| Brand |
Membrane Target Systems
|
| Buffer/Solvent |
50 mM Tris-HCL (pH 7.4), 0.5mM EDTA, 10mM MgCl2, 10% sucrose
|
| G-Alpha Natural Receptor |
Gi/Go
|
| Host Cell Line |
CHO-K1
|
| Host Species |
Human
|
| Product Group |
Membrane Preparation
|
| Receptor |
GABA
|
| Shipping Conditions |
Shipped in Dry Ice
|
| Target Class |
GPCR
|
| Therapeutic Area |
Central Nervous System
|
| Unit Size |
400 units
|
| Validation |
Binding
|
Resources
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Brochure
GPCRs: the pathway to discovery
G protein coupled-receptors (GPCRs) are one of the most intensively studied drug targets, with up to one-third of all marketed...
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