Glucagon-like peptide-1 (GLP-1), labeled with 125I. GLP-1 is a peptide hormone involved in secretion of insulin, and binds and activates GLP-1 receptors, a member of the glucagon receptor family of GPCRs.
| Feature | Specification |
|---|---|
| Fresh Lot Days | First Monday of each month |
| Label Position | Nominally Labeled |
| Molecular Weight | ~3298 |
| Receptor | グルカゴン |
Glucagon-like peptide-1 (GLP-1), labeled with 125I. GLP-1 is a peptide hormone involved in secretion of insulin, and binds and activates GLP-1 receptors, a member of the glucagon receptor family of GPCRs.
50 µCi Quantities of GLP-1 (7-36), [125I]- are available for your research.
We offer radioligands and radiolabeled biomolecules to use as tracers, for radioimmunoassays (RIAs), for autoradiographic visualization, or for performing saturation and competition radioligand binding assays to determine receptor expression levels (Bmax), dissociation constants (Kd), association and dissociation rates (kon and koff), and inhibitor constants (Ki) for a variety of receptors. We develop our radioligands to the highest specific activity possible and provide high purity resulting in low non-specific binding products. Each of our ultra-pure radiolabeled compounds is fully characterized for pharmacological action and validated in binding assays.
Radiochemicals remain the most sensitive method for probing binding biology; yielding unprecedented sensitivity gives results that technicians and scientists can trust. For over 50 years, Revvity has been a leading supplier of New England Nuclear (NEN) radiochemicals, liquid scintillation cocktails, vials and nuclear counting detection instruments.
References for NEX308:
| Molecular Weight |
~3298
|
|---|---|
| Specific Activity |
2200 Ci/mmol (81.4 TBq/mmol)
|
| CAS Number |
107444-51-9
|
| Application |
Drug Discovery & Development
|
|---|---|
| Brand |
NEN Radiochemicals
|
| Buffer/Solvent |
50 MM Sodium Acetate at pH4 with 50mm L-Ascorbic Acid, 50mm N-Acetylmethionine, 5% Sucrose and 0.25% BSA
|
| Detection Modality |
Radiometric
|
| Fresh Lot Days |
First Monday of each month
|
| Label Position |
Nominally Labeled
|
| Molecular Formula |
C149H226N40O45
|
| Packaging |
NENSure vial
|
| Radioisotope |
125I
|
| Receptor |
Glucagon
|
| Shipping Information |
Shipped on Dry Ice
|
| Shipping Conditions |
Shipped in Dry Ice
|
| Special Ordering Information |
This is a radioactive product - shipping address must have a license to receive radioactive materials.
|
| Storage Conditions |
-20°C
|
| Therapeutic Area |
Gastrointestinal
|
| Unit Size |
50 µCi
|
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