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LANCE Ultra Anti-methyl-Arg Eu-Antibody, 10 µg
LANCE Ultra Anti-methyl-Arg Eu-Antibody, 10 µg
Lance Ultra Antibody vial
| Feature | Specification |
|---|---|
| Application | Biochemical Enzymatic Assay |
For research use only. Not for use in diagnostic procedures. All products to be used in accordance with applicable laws and regulations including without limitation, consumption, and disposal requirements under European REACH regulations (EC 1907/2006).
LANCE Ultra Anti-methyl-Arg Eu-Antibody, 10 µg
Lance Ultra Antibody vial
LANCE Ultra Anti-methyl-Arg Eu-Antibody, 10 µg
Product information
Overview
The LANCE® Ultra Europium-anti-methyl-Histone H3/H4 Arginine (H3/H4Rme pan) antibody was used for the development and optimization of a PRMT4 methylation assay using a biotinylated Histone H3 peptide as substrate. A technical note describing the assay is available in our product literature.
Formats:
- 10 µg = 1,500 assay points (384-well assay format)
- 100 µg = 15,000 assay points (384-well format)
Proven, cost-efficient LANCE Ultra reagents can be used to quantitate peptide modifications, detecting specific meythylation and acetylation states. No wash, homogenous LANCE Ultra reagents are HTS friendly - design your own epigenetics screening strategy for greatest efficiency.
Epigenetic enzymatic assays are optimized using a biotinylated histone H3-derived peptide as substrate. The modified peptide is captured by the Eu-labeled antibody (Ab) and ULight-Streptavidin (SA) which bring the Eu donor and ULight acceptor dye molecules into close proximity. Upon irradiation at 320 or 340 nm, the energy from the Eu donor is transferred to the ULight acceptor dye which, in turn, generates light at 665 nm. The intensity of the light emission is proportional to the level of biotinylated substrate modification.
Specifications
| Application |
Biochemical Enzymatic Assay
|
|---|---|
| Automation Compatible |
Yes
|
| Brand |
LANCE Ultra
|
| Conjugates |
Anti-methyl arginine
|
| Detection Modality |
LANCE
|
| Fluorophore |
Eu-W1024
|
| Molecular Modification |
Methylation
|
| Product Group |
Antibody
|
| Shipping Conditions |
Shipped in Dry Ice
|
| Target Class |
Epigenetics
|
| Technology |
TR-FRET
|
| Unit Size |
10 µg
|
Resources
Are you looking for resources, click on the resource type to explore further.
Whitepaper
Epigenetic modifications and how they relate to cancer development and therapy
Epigenetic modifications in cancer
The field of epigenetics has revealed revolutionary methods for understanding heredity...
Product Info
LANCE and LANCE Ultra TR-FRET technology product list
LANCE™ Ultra TR-FRET is a no-wash proximity assay technology that combines the benefits of time resolution (TR) with fluorescence...
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