Allogeneic stem cell transplantation serves as a critical treatment for blood cancers and hematological diseases, with over 25,000 procedures performed globally each year. DKMS Life Science Lab, based in Dresden, Germany, operates as part of one of the world's largest donor networks, maintaining a registry of 12.5 million donors across seven countries.

The laboratory processes up to 100,000 buccal swabs and blood samples monthly with the chemagic™ workflow for initial HLA testing for possible positive matches. This high-volume operation requires consistent DNA extraction quality to support accurate downstream NGS-based HLA typing.

A decade of trusted performance

• 10+ years of consistent operation
• 10+ million samples successfully processed
• 1.49 μg median DNA yield per buccal swab with full locus coverage

"More than 10 years ago, we chose chemagen instruments and reagents for isolating DNA from blood or buccal swabs. After performing HLA genotyping on over 10 million samples, we remain extremely satisfied with this decision and the consistent performance." — Vinzenz Lange, DKMS Life Science Lab, Germany

Whether you're scaling genomics research, expanding testing capabilities, or optimizing high-throughput workflows, this case study demonstrates how the right technology partnership can be.

Get the full technical details on how DKMS Life Science Lab achieved industrial-scale DNA extraction with uncompromising quality. Learn about their custom workflow optimization, cost-reduction strategies, and the partnership approach.

For research use only. Not for use in diagnostic procedures.