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Application Note
FOXO1 in Non-Alcoholic Fatty Liver Disease
HTRF™ application note
Non-alcoholic fatty liver disease (NAFLD) includes a range of liver conditions unrelated to alcohol consumption that results in inflammation and fibrosis. NAFLD may progress to non-alcoholic steatohepatitis (NASH), cirrhosis, or liver failure; and is closely linked to metabolic syndromes through activation of glucose and lipogenesis-regulating transcription factors, such as FOXO1.
Download this complimentary application note to explore the use of an HTRF assay for the evaluation of FOXO1 in a fatty liver disease model and evaluate:
- Pro-inflammatory cytokine activation
- The benefits of HTRF assays compared to western blot
- A model system for fatty liver disease and insulin resistance
For research use only. Not for use in diagnostic procedures.
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FOXO1 in Non-Alcoholic Fatty Liver Disease