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Application Note
Download your application note on nuclear receptor ligand identification with HTRF
Dive deeper into NASH investigation
Nuclear Receptors (NRs) regulate gene transcription by DNA binding. Interaction of NRs with an agonist triggers conformational changes and enables the recruitment of coactivators (CoA), leading to gene transcription. The activity of several NRs has been associated to NAFLD, bringing about the emergence of new therapeutic targets in NASH.
Now, thanks to HTRF technology, you can monitor NR/CoA recruitment easily. With this application note you will:
- Benefit from HTRF technology in your research to identify potent NR ligands
- Discover the potential of HTRF PPi reagents to revolutionize your research
- Build robust and convenient NR/CoA recruitment assays for your research
For research use only. Not for use in diagnostic procedures.
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Download Resource
Download your application note on nuclear receptor ligand identification with HTRF