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Literature - Publication Review
Clinically translatable cytokine delivery platform for eradication of intraperitoneal tumors
Proinflammatory cytokine interleukin-2 (IL-2) is of particular interest for cancer immunotherapy as it plays a critical role in the regulation of immune cells such as T cells. Although proinflammatory cytokines have been used to treat various cancers including metastatic melanoma and renal carcinomas, it has a short blood half-life and the high-dose infusion regimens required result in off-target effects and toxicity in patients.
Read this publication review to learn how researchers used a clinically translatable cytokine delivery platform in an ovarian mouse model validated using non-invasive, longitudinal in vivo optical imaging.
For research use only. Not for use in diagnostic procedures.
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Clinically translatable cytokine delivery platform for eradication of intraperitoneal tumors