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    • Vanadis NIPT System

Vanadis NIPT System

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Easy. Precise. Cost-effective.

Vanadis™ NIPT system is an automated cell-free DNA testing platform designed to make noninvasive prenatal testing accessible to more women – and more cost-effective for your laboratory.


For in vitro diagnostic use. This product is only available where licensed in accordance with law. Please contact your local representative for availability.

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revvity vanadis system
  • Quick links
  • Overview
  • Workflow
  • Benefits
  • Kits
  • Software
  • Related products
  • Featured resources

Walkaway automation for greater efficiency

With Vanadis technology, all the critical steps are automated, starting with pipetting steps to reduce manual errors. Plasma volumes are monitored by camera to avoid contamination by the buffy coat, and samples and reagents are barcoded for complete tracking throughout the workflow. Our software guides you through the process, with user-friendly touchscreens, enabling remote workflow management for ease of use. Easy to integrate, our software is designed for LIMS connectivity, reducing manual errors while simplifying data management.

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vanadis-nipt-system-biochemistry

Groundbreaking cfDNA technology: No PCR, no sequencing

Vanadis is the only NIPT screening platform to enable targeted cfDNA analysis without PCR, instead directly capturing target fragments and labeling them for counting. A proprietary nanofilter plate then captures labeled molecules for imaging, eliminating the need for data-intensive steps such as DNA sequencing, microarrays, and microfluidics.

Workflow: Streamlined workflow from primary tube to final result

Screen for the risk of trisomies 21, 18, 13 & sex chromosome aneuploidies as well as fetal sex determination with Vanadis NIPT. By targeting thousands of chromosomal sequences, the Vanadis system can bring high precision non-invasive prenatal testing to your lab, counting an average of 650,000 molecules per chromosome.

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Benefits for your laboratory

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Easy to use. Easy to learn

Walkaway automation minimizes hands-on time and allows for quicker test results, available within 2-3 days.

scalable-platform

Scalable platform

Requiring only a single technician to run up to 14 000 samples per year, Vanadis empowers laboratories under ever-increasing workloads.

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High-precision technology

Designed to deliver high-precision measurements to improve the detection and false positive rates while minimizing the no-call rate.

Kits: Proven performance

Studies have demonstrated that the Vanadis NIPT system could improve detection and false positive rates, while minimizing the number of no-calls.

Products comprising the Vanadis NIPT system are CE-marked in vitro diagnostic products in accordance with European directive 98/79/EC.

  Sample outcome
Vanadis NIPT result

Trisomy 21

Trisomy 18

Trisomy 13

SCA
Detection rate (95% CI)

99%

(99/100)

(94.6%-100.0%)

92.9%

(26/28)

(76.5%-99.1%)

88.9%

(16/18)

(65.3%-98.6%)

84.0%

(21/25)

(63.9%-95.5%)

False positive rate (95% CI)

0.0%

(0/2032)

(0.0%-0.18%)

0.4%

(8/2032)

(0.17%-0.77%)

0.3%

(5/2032)

(0.08%-0.57%)

1.0%

(20/2015)

(0.6%-1.5%)

Observed no-call rate for 21/28/13 after first pass: 0.95%

 

Observed no-call rate for SCA after first pass: 1.13%

 


Source: Vanadis Core™ Reagent Cartridge II, kit insert Version #1.

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Leading risk calculation software

open_labLady

LifeCycle™ software

Vanadis™ NIPT system includes System Software and trusted LifeCycle™ software, the complete data management solution for prenatal screening laboratories. With a simple and flexible user interface and a performance monitoring dashboard that enables access from any current Web browser, these software provide the reliability and support laboratories can rely on.

Learn more

Related products

LC logo
LifeCycle 7.0 Software for Prenatal Screening
Part number: 5015-7000
View details
Lifecycle software
LifeCycle 7.0 with PC and System Software
Part number: 2028-8030
View details
Core reagent cartridge
Vanadis Core T21/T18/T13 Reagent Cartridge
Part number: 3222-001B
View details
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Featured resources

Brochure

Vanadis NIPT system – laboratory brochure

Learn more
Flyer

Vanadis NIPT – for clinicians

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Flyer

Vanadis NIPT – for patients

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